What is Global Genetically Engineered Mouse Model (GEMM) Market?
The Global Genetically Engineered Mouse Model (GEMM) Market is a specialized sector within the broader field of biotechnology and biomedical research. Genetically engineered mouse models are mice that have had their DNA altered through genetic engineering techniques to study human diseases, genetic functions, and drug responses. These models are invaluable for researchers because they can mimic human disease conditions, allowing scientists to observe the progression of diseases and test potential treatments in a controlled environment. The market for GEMMs is driven by the increasing demand for personalized medicine, advancements in genetic engineering technologies, and the growing prevalence of chronic diseases. Researchers and pharmaceutical companies rely heavily on these models to accelerate the development of new drugs and therapies, making the GEMM market a critical component of modern medical research. The market is characterized by a variety of players, including academic institutions, research organizations, and biotech companies, all contributing to the development and utilization of these sophisticated models.
Transgenic Mice, Knockout Mice, Others in the Global Genetically Engineered Mouse Model (GEMM) Market:
Transgenic mice, knockout mice, and other genetically engineered mouse models play distinct roles in the Global Genetically Engineered Mouse Model (GEMM) Market. Transgenic mice are created by introducing foreign genes into their genome, which can result in the expression of new traits or the study of gene functions. These mice are particularly useful for studying gene regulation, cancer, and other complex diseases. For example, researchers can insert a human gene associated with a particular disease into a mouse to observe how it affects the mouse's biology and to test potential treatments. Knockout mice, on the other hand, are engineered to have one or more of their genes "knocked out" or deactivated. This allows scientists to study the effects of losing a specific gene's function, providing insights into gene roles and the mechanisms of diseases. Knockout mice are widely used in research on genetic disorders, metabolic diseases, and immune system functions. Other types of genetically engineered mouse models include conditional knockout mice, where genes can be deactivated in specific tissues or at particular developmental stages, and humanized mice, which have been modified to carry human genes, tissues, or cells. These models are crucial for studying human-specific diseases and for preclinical testing of new drugs. The diversity of GEMMs allows researchers to choose the most appropriate model for their specific research needs, enhancing the precision and relevance of their studies. The development and use of these models require sophisticated genetic engineering techniques, including CRISPR/Cas9, which has revolutionized the field by making gene editing more efficient and accessible. The GEMM market is supported by a robust infrastructure of breeding facilities, genetic engineering services, and specialized laboratories that ensure the availability and quality of these models. As the demand for more accurate and human-relevant models continues to grow, the GEMM market is expected to expand, driven by ongoing advancements in genetic engineering and a deeper understanding of human genetics.
Basic Research, Drug Discovery, Toxicity Test, Hereditary Disease Study, Others in the Global Genetically Engineered Mouse Model (GEMM) Market:
The Global Genetically Engineered Mouse Model (GEMM) Market finds extensive usage in various research areas, including basic research, drug discovery, toxicity testing, hereditary disease studies, and others. In basic research, GEMMs are used to understand fundamental biological processes and gene functions. By manipulating specific genes, researchers can observe the resulting phenotypic changes and gain insights into gene regulation, developmental biology, and disease mechanisms. In drug discovery, GEMMs are indispensable for preclinical testing of new drugs. They provide a reliable platform to evaluate the efficacy and safety of potential therapeutics before they proceed to human clinical trials. These models help in identifying drug targets, understanding drug metabolism, and predicting potential side effects. Toxicity testing is another critical application of GEMMs, where they are used to assess the toxicological profiles of new compounds. By studying the effects of these compounds on genetically engineered mice, researchers can predict their potential toxicity in humans, ensuring safer drug development. Hereditary disease studies benefit significantly from GEMMs, as these models can be engineered to carry human disease genes, allowing researchers to study the genetic basis of diseases such as cystic fibrosis, muscular dystrophy, and various cancers. This enables the development of targeted therapies and personalized medicine approaches. Other applications of GEMMs include studying infectious diseases, neurological disorders, and immune system functions. The versatility and precision of GEMMs make them invaluable tools in biomedical research, contributing to significant advancements in our understanding of human health and disease. The continuous development of new genetic engineering techniques and the increasing availability of diverse mouse models are expected to further enhance the capabilities and applications of GEMMs in the future.
Global Genetically Engineered Mouse Model (GEMM) Market Outlook:
The global Genetically Engineered Mouse Model (GEMM) market was valued at US$ 2919.7 million in 2023 and is anticipated to reach US$ 4728.6 million by 2030, witnessing a CAGR of 6.5% during the forecast period 2024-2030. This market growth reflects the increasing demand for advanced research models in the biomedical field. The rising prevalence of chronic diseases, the need for personalized medicine, and advancements in genetic engineering technologies are key factors driving this growth. Researchers and pharmaceutical companies are increasingly relying on GEMMs to accelerate drug development and improve the understanding of disease mechanisms. The market is characterized by a diverse range of players, including academic institutions, research organizations, and biotech companies, all contributing to the development and utilization of these sophisticated models. The continuous advancements in genetic engineering techniques, such as CRISPR/Cas9, are expected to further drive the growth of the GEMM market, providing researchers with more precise and efficient tools for studying human diseases and developing new therapies.
| Report Metric | Details |
| Report Name | Genetically Engineered Mouse Model (GEMM) Market |
| Accounted market size in 2023 | US$ 2919.7 million |
| Forecasted market size in 2030 | US$ 4728.6 million |
| CAGR | 6.5% |
| Base Year | 2023 |
| Forecasted years | 2024 - 2030 |
| Segment by Type |
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| Segment by Application |
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| Consumption by Region |
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| By Company | The Jackson Laboratory, Charles River Laboratories, Taconic Biosciences, Envigo, Janvier Labs, GemPharmatech, GenOway, Applied StemCell, Fred Hutch, Mary Lyon Centre |
| Forecast units | USD million in value |
| Report coverage | Revenue and volume forecast, company share, competitive landscape, growth factors and trends |
